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The Optimized Women Podcast is where high-performing women come to take control of their health. Hosted by Orshi McNaughton, FDN-P, HHP, this show cuts through the noise of outdated medical advice with real, science-backed strategies built for female physiology. From hormones and metabolism to peptides, performance, and longevity—this is your no-BS guide to optimizing your body from the inside out.
Episodes

Tuesday Feb 04, 2025
Ep. 9: Women’s Health Research: Closing the Gender Gap
Tuesday Feb 04, 2025
Tuesday Feb 04, 2025
Women’s health research has historically overlooked critical differences in female biology. In this episode, Katie Moore and Dr. Mackenzie De Jesus join me to uncover the persistent gender gap in health studies. We discuss the implications of male-centric research, the rise of wearable health tech, and how women can take charge of their health with personalized solutions. Discover how new technologies and innovative studies are shaping the future of women’s health research.
👇 FREE GLP-1 MINI COURSE 👇
Instant access to my training on weight-loss peptides—discover top strategies for body recomposition, optimal dosing, and hormone balancing to safely reach your goals! 🚀 https://www.optimizedwomen.com/courses/glp-1
🔑 KEY TOPICS 🔑
- Why women have been historically excluded from health research
- The consequences of applying male-centric data to female health
- How wearables like Oura and Whoop are empowering women to biohack their health
- The role of personalized research in addressing unique female challenges
- How to participate in clinical studies through Reputable Health
🕐 TIMESTAMPS 🕐
[00:00] Introduction to Women’s Health Research
[01:13] Meet Katie Moore and Dr. Mackenzie De Jesus
[02:57] How autoimmune issues uniquely affect women
[05:56] Male-centric health research: The historical context
[11:21] Wearable devices and women’s health
[16:26] Using personalized health data for better outcomes
[25:10] The impact of gender-specific research on health care
[33:38] Participating in health studies with Reputable Health
🎙️ GUESTS 🎙️
Katie Moore and Dr. Mackenzie De Jesus
Join Women's Health Study: https://www.reputable.health/orshi
Instagram: https://www.instagram.com/reputablehealth
LinkedIn: https://www.linkedin.com/company/reputable-health
🌐 LET'S CONNECT 🌐
Host: Orshi McNaughton
Podcast Links: https://linktr.ee/optimizedwomen
YouTube Channel: https://www.youtube.com/@optimizedwomen
Instagram: https://www.instagram.com/optimizedwomen
👇 FREE GLP-1 MINI COURSE 👇
Instant access to my training on weight-loss peptides—discover top strategies for body recomposition, optimal dosing, and hormone balancing to safely reach your goals! 🚀 https://www.optimizedwomen.com/courses/glp-1
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This podcast is for informational purposes only and is not a substitute for professional medical advice. Always consult a healthcare provider for personalized health guidance.
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